MMP-10 Regulates Collagenolytic Activity of Alternatively Activated Resident Macrophages

MMP-10 is expressed by macrophages and epithelium in response to injury, but its functions in wound repair are unknown. We observed increased collagen deposition and skin stiffness in Mmp10(−/−) wounds with no difference in collagen expression or re-epithelialization. Increased collagen deposition i...

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Bibliografske podrobnosti
izdano v:J Invest Dermatol
Main Authors: Rohani, Maryam G., McMahan, Ryan S., Razumova, Maria V., Hertz, Angie L., Cieslewicz, Maryelise, Pun, Suzie H., Regnier, Michael, Wang, Ying, Birkland, Timothy P., Parks, William C.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567949/
https://ncbi.nlm.nih.gov/pubmed/25927164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.167
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