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Gas-Phase Amidation of Carboxylic Acids with Woodward’s Reagent K Ions

Gas-phase amidation of carboxylic acids in multiply-charged peptides is demonstrated via ion/ion reactions with Woodward’s reagent K (wrk) in both positive and negative mode. Woodward’s reagent K, N-ethyl-3-phenylisoxazolium-3′-sulfonate, is a commonly used reagent that activates carboxylates to for...

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Detalhes bibliográficos
Publicado no:J Am Soc Mass Spectrom
Main Authors: Peng, Zhou, Pilo, Alice L., Luongo, Carl A., McLuckey, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567925/
https://ncbi.nlm.nih.gov/pubmed/26122523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-015-1209-8
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