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Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts

BACKGROUND: Hematopoietic Stem Cell Transplantation (HSCT) is known to induce the inhibitory immune receptor NKG2A on NK cells of donor origin. This occurs in allogeneic recipients, in both the haploidentical and HLA-matched settings. METHODS: To gain further insight, not only NKG2A, but also the ac...

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Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Picardi, Alessandra, Mengarelli, Andrea, Marino, Mirella, Gallo, Enzo, Benevolo, Maria, Pescarmona, Edoardo, Cocco, Roberta, Fraioli, Rocco, Tremante, Elisa, Petti, Maria Concetta, De Fabritiis, Paolo, Giacomini, Patrizio
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567793/
https://ncbi.nlm.nih.gov/pubmed/26361968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0213-y
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