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Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts

BACKGROUND: Hematopoietic Stem Cell Transplantation (HSCT) is known to induce the inhibitory immune receptor NKG2A on NK cells of donor origin. This occurs in allogeneic recipients, in both the haploidentical and HLA-matched settings. METHODS: To gain further insight, not only NKG2A, but also the ac...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Picardi, Alessandra, Mengarelli, Andrea, Marino, Mirella, Gallo, Enzo, Benevolo, Maria, Pescarmona, Edoardo, Cocco, Roberta, Fraioli, Rocco, Tremante, Elisa, Petti, Maria Concetta, De Fabritiis, Paolo, Giacomini, Patrizio
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567793/
https://ncbi.nlm.nih.gov/pubmed/26361968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0213-y
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