Profiling the Essential Nature of Lipid Metabolism in Asexual Blood and Gametocyte Stages of Plasmodium falciparum

During its life cycle, Plasmodium falciparum undergoes rapid proliferation fueled by de novo synthesis and acquisition of host cell lipids. Consistent with this essential role, Plasmodium lipid synthesis enzymes are emerging as potential drug targets. To explore their broader potential for therapeut...

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Détails bibliographiques
Publié dans:Cell Host Microbe
Auteurs principaux: Gulati, Sonia, Ekland, Eric H., Ruggles, Kelly V., Chan, Robin B., Jayabalasingham, Bamini, Zhou, Bowen, Mantel, Pierre-Yves, Lee, Marcus C. S., Spottiswoode, Natasha, Coburn-Flynn, Olivia, Hjelmqvist, Daisy, Worgall, Tilla S., Marti, Matthias, Di Paolo, Gilbert, Fidock, David A.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567697/
https://ncbi.nlm.nih.gov/pubmed/26355219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.08.003
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