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Reversible Conformational Change in the Plasmodium falciparum Circumsporozoite Protein Masks Its Adhesion Domains
The extended rod-like Plasmodium falciparum circumsporozoite protein (CSP) is comprised of three primary domains: a charged N terminus that binds heparan sulfate proteoglycans, a central NANP repeat domain, and a C terminus containing a thrombospondin-like type I repeat (TSR) domain. Only the last t...
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Publié dans: | Infect Immun |
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Auteurs principaux: | , , , , , , , , , , , , , , , , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
American Society for Microbiology
2015
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4567636/ https://ncbi.nlm.nih.gov/pubmed/26169272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02676-14 |
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