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The Poly-γ-d-Glutamic Acid Capsule Surrogate of the Bacillus anthracis Capsule Is a Novel Toll-Like Receptor 2 Agonist

Bacillus anthracis is a pathogenic Gram-positive bacterium that causes a highly lethal infectious disease, anthrax. The poly-γ-d-glutamic acid (PGA) capsule is one of the major virulence factors of B. anthracis, along with exotoxins. PGA enables B. anthracis to escape phagocytosis and immune surveil...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Jeon, Jun Ho, Lee, Hae-Ri, Cho, Min-Hee, Park, Ok-Kyu, Park, Jungchan, Rhie, Gi-eun
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567625/
https://ncbi.nlm.nih.gov/pubmed/26195551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00888-15
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