Poly-γ-Glutamate Capsule-Degrading Enzyme Treatment Enhances Phagocytosis and Killing of Encapsulated Bacillus anthracis

The poly-γ-d-glutamic acid capsule confers antiphagocytic properties on Bacillus anthracis and is essential for virulence. In this study, we showed that CapD, a γ-polyglutamic acid depolymerase encoded on the B. anthracis capsule plasmid, degraded purified capsule and removed the capsule from the su...

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Detalhes bibliográficos
Principais autores: Scorpio, Angelo, Chabot, Donald J., Day, William A., O'Brien, David K., Vietri, Nicholas J., Itoh, Yoshifumi, Mohamadzadeh, Mansour, Friedlander, Arthur M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1797643/
https://ncbi.nlm.nih.gov/pubmed/17074794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00706-06
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