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Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein
Invading viral DNA can be recognized by the host cytosolic DNA sensor, cyclic GMP-AMP (cGAMP) synthase (cGAS), resulting in production of the second messenger cGAMP, which directs the adaptor protein STING to stimulate production of type I interferons (IFNs). Although several DNA viruses are sensed...
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| Publicat a: | Cell Host Microbe |
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| Autors principals: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4567405/ https://ncbi.nlm.nih.gov/pubmed/26320998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2015.07.015 |
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