Enriched Bone Marrow Derived Disseminated Neuroblastoma Cells Can Be a Reliable Source for Gene Expression Studies—A Validation Study

BACKGROUND: Metastases in the bone marrow (BM) in form of disseminated tumor cells (DTCs) are frequent events at diagnosis and also at relapse in high-risk neuroblastoma patients. The frequently highly diluted occurrence of DTCs requires adequate enrichment strategies to enable their detailed charac...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Rifatbegovic, Fikret, Abbasi, M. Reza, Taschner-Mandl, Sabine, Kauer, Maximilian, Weinhäusel, Andreas, Handgretinger, Rupert, Ambros, Peter F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567134/
https://ncbi.nlm.nih.gov/pubmed/26360775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137995
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