Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids

Multicellular tumor spheroids represent a 3D in vitro model that mimics solid tumor essential properties including assembly and development of extracellular matrix and nutrient, oxygen and proliferation gradients. In the present study, we analyze the impact of 3D spatial organization of HER2-overexp...

Full description

Saved in:
Bibliographic Details
Published in:PLoS One
Main Authors: Rodríguez, Cristina E., Reidel, Sara I., Bal de Kier Joffé, Elisa D., Jasnis, Maria A., Fiszman, Gabriel L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567133/
https://ncbi.nlm.nih.gov/pubmed/26360292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137920
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items