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Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids.

Multicellular tumor spheroids represent a 3D in vitro model that mimics solid tumor essential properties including assembly and development of extracellular matrix and nutrient, oxygen and proliferation gradients. In the present study, we analyze the impact of 3D spatial organization of HER2-overexp...

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Bibliografske podrobnosti
Main Authors: Cristina E Rodríguez, Sara I Reidel, Elisa D Bal de Kier Joffé, Maria A Jasnis, Gabriel L Fiszman
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2015-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4567133?pdf=render
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