Downregulation of PHEX in multibacillary leprosy patients: observational cross-sectional study

BACKGROUND: Peripheral nerve injury and bone lesions, well known leprosy complications, lead to deformities and incapacities. The phosphate-regulating gene with homologies to endopeptidase on the X chromosome (PHEX) encodes a homonymous protein (PHEX) implicated in bone metabolism. PHEX/PHEX alterat...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Transl Med
Main Authors: Silva, Sandra R. Boiça, Illarramendi, Ximena, Tempone, Antonio J., Silva, Pedro H. L., Nery, José A. C., Monteiro, Alexandra M. V., Pessolani, Maria Cristina V., Boasquevisque, Edson, Sarno, Euzenir N., Pereira, Geraldo M. B., Esquenazi, Danuza
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2015
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566286/
https://ncbi.nlm.nih.gov/pubmed/26362198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0651-5
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