Downregulation of PHEX in multibacillary leprosy patients: observational cross-sectional study

BACKGROUND: Peripheral nerve injury and bone lesions, well known leprosy complications, lead to deformities and incapacities. The phosphate-regulating gene with homologies to endopeptidase on the X chromosome (PHEX) encodes a homonymous protein (PHEX) implicated in bone metabolism. PHEX/PHEX alterat...

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Bibliografiska uppgifter
I publikationen:J Transl Med
Huvudupphovsmän: Silva, Sandra R. Boiça, Illarramendi, Ximena, Tempone, Antonio J., Silva, Pedro H. L., Nery, José A. C., Monteiro, Alexandra M. V., Pessolani, Maria Cristina V., Boasquevisque, Edson, Sarno, Euzenir N., Pereira, Geraldo M. B., Esquenazi, Danuza
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2015
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566286/
https://ncbi.nlm.nih.gov/pubmed/26362198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0651-5
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