Synapse-Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport in Caenorhabditis elegans

The functional integrity of neurons requires the bidirectional active transport of synaptic vesicles (SVs) in axons. The kinesin motor KIF1A transports SVs from somas to stable SV clusters at synapses, while dynein moves them in the opposite direction. However, it is unclear how SV transport is regu...

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Udgivet i:Genetics
Main Authors: Edwards, Stacey L., Yorks, Rosalina M., Morrison, Logan M., Hoover, Christopher M., Miller, Kenneth G.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2015
Fag:
Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566279/
https://ncbi.nlm.nih.gov/pubmed/26354975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.177337
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