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Histone Core Phosphorylation Regulates DNA Accessibility

Nucleosome unwrapping dynamics provide transient access to the complexes involved in DNA transcription, repair, and replication, whereas regulation of nucleosome unwrapping modulates occupancy of these complexes. Histone H3 is phosphorylated at tyrosine 41 (H3Y41ph) and threonine 45 (H3T45ph). H3Y41...

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Foilsithe in:J Biol Chem
Main Authors: Brehove, Matthew, Wang, Tao, North, Justin, Luo, Yi, Dreher, Sarah J., Shimko, John C., Ottesen, Jennifer J., Luger, Karolin, Poirier, Michael G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566235/
https://ncbi.nlm.nih.gov/pubmed/26175159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.661363
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