ETS-related Transcription Factors ETV4 and ETV5 Are Involved in Proliferation and Induction of Differentiation-associated Genes in Embryonic Stem (ES) Cells

The pluripotency and self-renewal capacity of embryonic stem (ES) cells is regulated by several transcription factors. Here, we show that the ETS-related transcription factors Etv4 and Etv5 (Etv4/5) are specifically expressed in undifferentiated ES cells, and suppression of Oct3/4 results in down-re...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Akagi, Tadayuki, Kuure, Satu, Uranishi, Kousuke, Koide, Hiroshi, Costantini, Frank, Yokota, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566222/
https://ncbi.nlm.nih.gov/pubmed/26224636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675595
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