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The miR-200 Family and Its Targets Regulate Type II Cell Differentiation in Human Fetal Lung
Type II cell differentiation and expression of the major surfactant protein, SP-A, in mid-gestation human fetal lung (HFL) are induced by cAMP and inhibited by TGF-β. cAMP induction of SP-A promoter activity is mediated by increased phosphorylation and DNA binding of thyroid transcription factor-1 (...
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| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4566216/ https://ncbi.nlm.nih.gov/pubmed/26203191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.636068 |
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