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The MicroRNA 29 Family Promotes Type II Cell Differentiation in Developing Lung

Lung alveolar type II cells uniquely synthesize surfactant, a developmentally regulated lipoprotein that is essential for breathing. Expression of the gene (SFTPA) encoding the major surfactant protein, SP-A, in midgestation human fetal lung (HFL) is dramatically induced by cyclic AMP (cAMP). cAMP i...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Guo, Wei, Benlhabib, Houda, Mendelson, Carole R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968214/
https://ncbi.nlm.nih.gov/pubmed/27215389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00096-16
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