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Substrate-bound Structures of Benzylsuccinate Synthase Reveal How Toluene Is Activated in Anaerobic Hydrocarbon Degradation

Various bacteria perform anaerobic degradation of small hydrocarbons as a source of energy and cellular carbon. To activate non-reactive hydrocarbons such as toluene, enzymes conjugate these molecules to fumarate in a radical-catalyzed, C—C bond-forming reaction. We have determined x-ray crystal str...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Funk, Michael A., Marsh, E. Neil G., Drennan, Catherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566215/
https://ncbi.nlm.nih.gov/pubmed/26224635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.670737
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