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Mechanism of Benzylsuccinate Synthase Probed by Substrate and Isotope Exchange
Benzylsuccinate synthase catalyzes the first step in the anaerobic metabolism of toluene through an unusual reaction in which toluene is added to fumarate to produce (R)-benzylsuccinate. We have exploited the broad substrate range of the enzyme to demonstrate that the enzyme can catalyze the exchang...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527060/ https://ncbi.nlm.nih.gov/pubmed/17165757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja067329q |
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