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Surfactant Dysfunction and Lung Inflammation in the Female Mouse Model of Lymphangioleiomyomatosis

Pulmonary lymphangioleiomyomatosis (LAM) is a rare lung disease caused by mutations of the tumor suppressor genes, tuberous sclerosis complex (TSC) 1 or TSC2. LAM affects women almost exclusively, and it is characterized by neoplastic growth of atypical smooth muscle–like TSC2-null LAM cells in the...

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Detalles Bibliográficos
Publicado en:Am J Respir Cell Mol Biol
Autores principales: Atochina-Vasserman, Elena N., Guo, Chang-Jiang, Abramova, Elena, Golden, Thea N., Sims, Michael, James, Melane L., Beers, Michael F., Gow, Andrew J., Krymskaya, Vera P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566108/
https://ncbi.nlm.nih.gov/pubmed/25474372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0224OC
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