Segmental Allergen Challenge Alters Multimeric Structure and Function of Surfactant Protein D in Humans

Rationale: Surfactant protein D (SP-D), a 43-kD collectin, is synthesized and secreted by airway epithelia as a dodecamer formed by assembly of four trimeric subunits. We have previously shown that the quaternary structure of SP-D can be altered during inflammatory lung injury through its modificati...

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Detalhes bibliográficos
Main Authors: Atochina-Vasserman, Elena N., Winkler, Carla, Abramova, Helen, Schaumann, Frank, Krug, Norbert, Gow, Andrew J., Beers, Michael F., Hohlfeld, Jens M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
Assuntos:
A. Asthma and Allergy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086753/
https://ncbi.nlm.nih.gov/pubmed/21131470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201004-0654OC
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