Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension

Hypoxic pulmonary vasoconstriction (HPV) is an important physiological response that optimizes the ventilation/perfusion ratio. Chronic hypoxia causes vascular remodeling, which is central to the pathogenesis of hypoxia-induced pulmonary hypertension (HPH). We have previously shown that Notch3 is up...

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Detaylı Bibliyografya
Yayımlandı:Am J Respir Cell Mol Biol
Asıl Yazarlar: Smith, Kimberly A., Voiriot, Guillaume, Tang, Haiyang, Fraidenburg, Dustin R., Song, Shanshan, Yamamura, Hisao, Yamamura, Aya, Guo, Qiang, Wan, Jun, Pohl, Nicole M., Tauseef, Mohammad, Bodmer, Rolf, Ocorr, Karen, Thistlethwaite, Patricia A., Haddad, Gabriel G., Powell, Frank L., Makino, Ayako, Mehta, Dolly, Yuan, Jason X.-J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2015
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4566064/
https://ncbi.nlm.nih.gov/pubmed/25569851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0235OC
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