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Effects of Emtricitabine/Tenofovir on Bone Mineral Density in HIV-Negative Persons in a Randomized, Double-Blind, Placebo-Controlled Trial

Background. Daily preexposure prophylaxis (PrEP) with oral emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) decreases the risk of human immunodeficiency virus (HIV) acquisition. Initiation of TDF decreases bone mineral density (BMD) in HIV-infected people. We report the effect of FTC/TDF on...

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Published in:Clin Infect Dis
Main Authors: Mulligan, Kathleen, Glidden, David V., Anderson, Peter L., Liu, Albert, McMahan, Vanessa, Gonzales, Pedro, Ramirez-Cardich, Maria Esther, Namwongprom, Sirianong, Chodacki, Piotr, de Mendonca, Laura Maria Carvalo, Wang, Furong, Lama, Javier R., Chariyalertsak, Suwat, Guanira, Juan Vicente, Buchbinder, Susan, Bekker, Linda-Gail, Schechter, Mauro, Veloso, Valdilea G., Grant, Robert M., Vargas, Lorena, Sanchez, Jorge, Mai, Chiang, Saokhieo, Pongpun, Murphy, Kerry, Gilmore, Hailey, Holland, Sally, Faber, Elizabeth, Duda, John, Bewerunge, Linda, Batist, Elizabeth, Hoskin, Christine, Brown, Ben, de Janeiro, Rio, Beppu-Yoshida, Carina, da Costa, Marcellus Dias, Assis de Jesus, Sergio Carlos, Grangeiro da Silva, Jose Roberto, Millan, Roberta, de Siqueira Hoagland, Brenda Regina, Martinez Fernandes, Nilo, da Silva Freitas, Lucilene, Grinsztejn, Beatriz, Pilotto, Jose, Bushman, Lane, Zheng, Jia-Hua, Anthony Guida, Louis, Kline, Brandon, Goicochea, Pedro, Manzo, Jonathan, Hance, Robert, McConnell, Jeff, Defechereux, Patricia, Levy, Vivian, Robles, Malu, Postle, Brian, Burns, David, Rooney, James
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565984/
https://ncbi.nlm.nih.gov/pubmed/25908682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/civ324
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