Strong Correlation Between Concentrations of Tenofovir (TFV) Emtricitabine (FTC) in Hair and TFV Diphosphate and FTC Triphosphate in Dried Blood Spots in the iPrEx Open Label Extension: Implications for Pre-exposure Prophylaxis Adherence Monitoring

Self-reported adherence to pre-exposure prophylaxis (PrEP) has limitations, raising interest in pharmacologic monitoring. Drug concentrations in hair and dried blood spots (DBS) are used to assess long-term-exposure; hair shipment/storage occurs at room temperature. The iPrEx Open Label Extension co...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Gandhi, Monica, Glidden, David V., Liu, Albert, Anderson, Peter L., Horng, Howard, Defechereux, Patricia, Guanira, Juan V., Grinsztejn, Beatriz, Chariyalertsak, Suwat, Bekker, Linda-Gail, Grant, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601920/
https://ncbi.nlm.nih.gov/pubmed/25895984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv239
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