Inhibition of MAP kinase/NF-kB mediated signaling and attenuation of lipopolysaccharide induced severe sepsis by cerium oxide nanoparticles

Sepsis is a life threatening disease that is associated with high mortality. Existing treatments have failed to improve survivability in septic patients. The purpose of this present study is to evaluate whether cerium oxide nanoparticles (CeO(2)NPs) can prevent lipopolysaccharide (LPS) induced sever...

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Bibliografske podrobnosti
izdano v:Biomaterials
Main Authors: Selvaraj, Vellaisamy, Nepal, Niraj, Rogers, Steven, Manne, Nandini D.P.K., Arvapalli, Ravikumar, Rice, Kevin M., Asano, Shinichi, Fankhanel, Erin, Ma, Jane J., Shokuhfar, Tolou, Maheshwari, Mani, Blough, Eric R.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565726/
https://ncbi.nlm.nih.gov/pubmed/25968464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.04.025
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