Inhibition of MAP kinase/NF-kB mediated signaling and attenuation of lipopolysaccharide induced severe sepsis by cerium oxide nanoparticles

Sepsis is a life threatening disease that is associated with high mortality. Existing treatments have failed to improve survivability in septic patients. The purpose of this present study is to evaluate whether cerium oxide nanoparticles (CeO(2)NPs) can prevent lipopolysaccharide (LPS) induced sever...

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Bibliographic Details
Published in:Biomaterials
Main Authors: Selvaraj, Vellaisamy, Nepal, Niraj, Rogers, Steven, Manne, Nandini D.P.K., Arvapalli, Ravikumar, Rice, Kevin M., Asano, Shinichi, Fankhanel, Erin, Ma, Jane J., Shokuhfar, Tolou, Maheshwari, Mani, Blough, Eric R.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565726/
https://ncbi.nlm.nih.gov/pubmed/25968464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.04.025
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