G Protein-Coupled Estrogen Receptor 1 Mediates Acute Estrogen-Induced Cardioprotection via MEK/ERK/GSK-3β Pathway after Ischemia/Reperfusion

Three types of estrogen receptors (ER) exist in the heart, Esr1, Esr2 and the G protein-coupled estrogen receptor 1, Gper1. However, their relative importance in mediating estrogen protective action is unknown. We found that, in the male mouse ventricle, Gper1 transcripts are three- and seventeen-fo...

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Publicat a:PLoS One
Autors principals: Kabir, Mohammad E., Singh, Harpreet, Lu, Rong, Olde, Bjorn, Leeb-Lundberg, L. M. Fredrik, Bopassa, Jean Chrisostome
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565659/
https://ncbi.nlm.nih.gov/pubmed/26356837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135988
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