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Therapeutic Implications of a Barrier-Based Pathogenesis of Atopic Dermatitis
Excessive Th2 cell signaling and IgE production play key roles in the pathogenesis of atopic dermatitis (AD). Yet, recent information suggests that the inflammation in AD instead is initiated by inherited insults to the barrier, including a strong association between mutations in FILAGGRIN and SPINK...
Enregistré dans:
| Publié dans: | Clin Rev Allergy Immunol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4565600/ https://ncbi.nlm.nih.gov/pubmed/21174234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12016-010-8231-1 |
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