Effect of Metformin vs Placebo on Weight and Metabolic Factors in NCIC CTG MA.32

BACKGROUND: Metformin may improve metabolic factors (insulin, glucose, leptin, highly sensitive C-reactive protein [hs-CRP]) associated with poor breast cancer outcomes. The NCIC Clinical Trials Group (NCIC CTG) MA.32 investigates effects of metformin vs placebo on invasive disease-free survival and...

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Publicado no:J Natl Cancer Inst
Main Authors: Goodwin, Pamela J., Parulekar, Wendy R., Gelmon, Karen A., Shepherd, Lois E., Ligibel, Jennifer A., Hershman, Dawn L., Rastogi, Priya, Mayer, Ingrid A., Hobday, Timothy J., Lemieux, Julie, Thompson, Alastair M., Pritchard, Kathleen I., Whelan, Timothy J., Mukherjee, Som D., Chalchal, Haji I., Oja, Conrad D., Tonkin, Katia S., Bernstein, Vanessa, Chen, Bingshu E., Stambolic, Vuk
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4565534/
https://ncbi.nlm.nih.gov/pubmed/25740979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv006
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