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Soluble CD4 enhances the efficacy of immunotoxins directed against gp41 of the human immunodeficiency virus.

Monoclonal antibodies specific for the gp120 or gp41 portions of the human immunodeficiency virus (HIV) envelope protein gp160 were conjugated to ricin A chain, and their immunotoxic activities against HIV-infected cells were evaluated in the presence or absence of soluble CD4 (sCD4). Immunotoxin ac...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Pincus, S H, McClure, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45654/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8419938/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.1.332
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