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Neutralization of divergent human immunodeficiency virus type 1 variants and primary isolates by IAM-41-2F5, an anti-gp41 human monoclonal antibody.

The antiviral characteristics of monoclonal antibody IAM-41-2F5 (2F5) were determined in cell culture. The antibody had been previously shown to bind a specific sequence, ELDKWA, within the external domain of the gp41 envelope glycoprotein human immunodeficiency virus type 1 (HIV-1). Selection by 2F...

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Detalhes bibliográficos
Main Authors: Conley, A J, Kessler, J A, Boots, L J, Tung, J S, Arnold, B A, Keller, P M, Shaw, A R, Emini, E A
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43574/
https://ncbi.nlm.nih.gov/pubmed/7512731
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