The multidrug resistance (mdr1) gene product functions as an ATP channel.

The multidrug resistance (mdr1) gene product, P-glycoprotein, is responsible for the ATP-dependent extrusion of a variety of compounds, including chemotherapeutic drugs, from cells. The data presented here show that cells with increased levels of the P-glycoprotein release ATP to the medium in propo...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Abraham, E H, Prat, A G, Gerweck, L, Seneveratne, T, Arceci, R J, Kramer, R, Guidotti, G, Cantiello, H F
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45650/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7678345/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.1.312
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