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The multidrug resistance (mdr1) gene product functions as an ATP channel.

The multidrug resistance (mdr1) gene product, P-glycoprotein, is responsible for the ATP-dependent extrusion of a variety of compounds, including chemotherapeutic drugs, from cells. The data presented here show that cells with increased levels of the P-glycoprotein release ATP to the medium in propo...

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Detalhes bibliográficos
Main Authors: Abraham, E H, Prat, A G, Gerweck, L, Seneveratne, T, Arceci, R J, Kramer, R, Guidotti, G, Cantiello, H F
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC45650/
https://ncbi.nlm.nih.gov/pubmed/7678345
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