Respiration and substrate transport rates as well as reactive oxygen species production distinguish mitochondria from brain and liver

BACKGROUND: Aberrant mitochondrial function, including excessive reactive oxygen species (ROS) production, has been implicated in the pathogenesis of human diseases. The use of mitochondrial inhibitors to ascertain the sites in the electron transport chain (ETC) resulting in altered ROS production c...

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Udgivet i:BMC Biochem
Main Authors: Gusdon, Aaron M., Fernandez-Bueno, Gabriel A., Wohlgemuth, Stephanie, Fernandez, Jenelle, Chen, Jing, Mathews, Clayton E.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564979/
https://ncbi.nlm.nih.gov/pubmed/26358560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12858-015-0051-8
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