mt-Nd2(a) Suppresses Reactive Oxygen Species Production by Mitochondrial Complexes I and III

Reactive oxygen species (ROS) play a critical role in the pathogenesis of human diseases. A cytosine to adenine transversion in the mitochondrially encoded NADH dehydrogenase subunit 2 (mt-ND2, human; mt-Nd2, mouse) gene results in resistance against type 1 diabetes and several additional ROS-associ...

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Bibliographic Details
Main Authors: Gusdon, Aaron M., Votyakova, Tatyana V., Mathews, Clayton E.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Metabolism and Bioenergetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447668/
https://ncbi.nlm.nih.gov/pubmed/18281288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708801200
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