Parathyroid hormone resets the cartilage circadian clock of the organ-cultured murine femur

BACKGROUND AND PURPOSE: The circadian clock governs endogenous day-night variations. In bone, the metabolism and growth show diurnal rhythms. The circadian clock is based on a transcription-translation feedback loop composed of clock genes including Period2 (Per2), which encodes the protein period c...

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Detalhes bibliográficos
Publicado no:Acta Orthop
Main Authors: Okubo, Naoki, Fujiwara, Hiroyoshi, Minami, Yoichi, Kunimoto, Tatsuya, Hosokawa, Toshihiro, Umemura, Yasuhiro, Inokawa, Hitoshi, Asada, Maki, Oda, Ryo, Kubo, Toshikazu, Yagita, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Informa Healthcare 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564788/
https://ncbi.nlm.nih.gov/pubmed/25765847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/17453674.2015.1029393
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