Exploring the Dynamics and Mutational Landscape of Riboregulation with a Minimal Synthetic Circuit in Living Cells

The regulation of gene expression, triggered by conformational changes in RNA molecules, is widely observed in cellular systems. Here, we examine this mode of control by means of a model-based design and construction of a fully synthetic riboregulatory device. We present a theoretical framework that...

Full description

Saved in:
Bibliographic Details
Published in:Biophys J
Main Authors: Rodrigo, Guillermo, Majer, Eszter, Prakash, Satya, Daròs, José-Antonio, Jaramillo, Alfonso, Poyatos, Juan F.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2015
Subjects:
Systems Biophysics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564674/
https://ncbi.nlm.nih.gov/pubmed/26331264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.07.021
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items