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De novo automated design of small RNA circuits for engineering synthetic riboregulation in living cells

A grand challenge in synthetic biology is to use our current knowledge of RNA science to perform the automatic engineering of completely synthetic sequences encoding functional RNAs in living cells. We report here a fully automated design methodology and experimental validation of synthetic RNA inte...

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Detalhes bibliográficos
Main Authors: Rodrigo, Guillermo, Landrain, Thomas E., Jaramillo, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458397/
https://ncbi.nlm.nih.gov/pubmed/22949707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203831109
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