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De novo automated design of small RNA circuits for engineering synthetic riboregulation in living cells

A grand challenge in synthetic biology is to use our current knowledge of RNA science to perform the automatic engineering of completely synthetic sequences encoding functional RNAs in living cells. We report here a fully automated design methodology and experimental validation of synthetic RNA inte...

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Bibliografiske detaljer
Main Authors: Rodrigo, Guillermo, Landrain, Thomas E., Jaramillo, Alfonso
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458397/
https://ncbi.nlm.nih.gov/pubmed/22949707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1203831109
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