A Kunjin Replicon Virus-like Particle Vaccine Provides Protection Against Ebola Virus Infection in Nonhuman Primates

The current unprecedented outbreak of Ebola virus (EBOV) disease in West Africa has demonstrated the urgent need for a vaccine. Here, we describe the evaluation of an EBOV vaccine candidate based on Kunjin replicon virus-like particles (KUN VLPs) encoding EBOV glycoprotein with a D637L mutation (GP/...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Pyankov, Oleg V., Bodnev, Sergey A., Pyankova, Olga G., Solodkyi, Vladislav V., Pyankov, Stepan A., Setoh, Yin Xiang, Volchkova, Valentina A., Suhrbier, Andreas, Volchkov, Viktor V., Agafonov, Alexander A., Khromykh, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564530/
https://ncbi.nlm.nih.gov/pubmed/25732811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv019
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