A Kunjin Replicon Virus-like Particle Vaccine Provides Protection Against Ebola Virus Infection in Nonhuman Primates

The current unprecedented outbreak of Ebola virus (EBOV) disease in West Africa has demonstrated the urgent need for a vaccine. Here, we describe the evaluation of an EBOV vaccine candidate based on Kunjin replicon virus-like particles (KUN VLPs) encoding EBOV glycoprotein with a D637L mutation (GP/...

詳細記述

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書誌詳細
出版年:J Infect Dis
主要な著者: Pyankov, Oleg V., Bodnev, Sergey A., Pyankova, Olga G., Solodkyi, Vladislav V., Pyankov, Stepan A., Setoh, Yin Xiang, Volchkova, Valentina A., Suhrbier, Andreas, Volchkov, Viktor V., Agafonov, Alexander A., Khromykh, Alexander A.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2015
主題:
Ebola and Marburg Viruses-Research, Outbreak Management, Epidemiology and Ecology
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564530/
https://ncbi.nlm.nih.gov/pubmed/25732811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv019
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