Kunjin Virus Replicon Vaccine Vectors Induce Protective CD8(+) T-Cell Immunity

The ability of self-replicating RNA (replicon) vaccine vectors derived from the Australian flavivirus Kunjin (KUN) to induce protective αβ CD8(+) T-cell responses was examined. KUN replicons encoding a model immunogen were delivered by three different vaccine modalities: (i) as naked RNA transcribed...

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Detalhes bibliográficos
Main Authors: Anraku, Itaru, Harvey, Tracey J., Linedale, Richard, Gardner, Joy, Harrich, David, Suhrbier, Andreas, Khromykh, Alexander A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136104/
https://ncbi.nlm.nih.gov/pubmed/11907219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.8.3791-3799.2002
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