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Kunjin Virus Replicon Vaccine Vectors Induce Protective CD8(+) T-Cell Immunity

The ability of self-replicating RNA (replicon) vaccine vectors derived from the Australian flavivirus Kunjin (KUN) to induce protective αβ CD8(+) T-cell responses was examined. KUN replicons encoding a model immunogen were delivered by three different vaccine modalities: (i) as naked RNA transcribed...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Anraku, Itaru, Harvey, Tracey J., Linedale, Richard, Gardner, Joy, Harrich, David, Suhrbier, Andreas, Khromykh, Alexander A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136104/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11907219/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.8.3791-3799.2002
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