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Atorvastatin and sildenafil decrease vascular TGF-β levels and MMP-2 activity and ameliorate arterial remodeling in a model of renovascular hypertension

Imbalanced matrix metalloproteinase (MMP)-2 activity and transforming growth factor expression (TGF-β) are involved in vascular remodeling of hypertension. Atorvastatin and sildenafil exert antioxidant and pleiotropic effects that may result in cardiovascular protection. We hypothesized that atorvas...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Redox Biol
मुख्य लेखकों: Guimarães, Danielle A., Rizzi, Elen, Ceron, Carla S., Martins-Oliveira, Alisson, Gerlach, Raquel F., Shiva, Sruti, Tanus-Santos, Jose E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564390/
https://ncbi.nlm.nih.gov/pubmed/26343345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.08.017
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