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Molecular Basis for the Mechanism of Constitutive CBP/p300 Coactivator Recruitment by CRTC1-MAML2 and its Implications in cAMP Signaling

The cyclic AMP response element binding protein (CREB) is a signal-dependent transcription factor that exerts its positive effects on gene transcription of a broad range of genes by recruiting coactivators including CREB-binding protein (CBP), its paralog p300, and the family of CRTC (CREB-regulated...

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Détails bibliographiques
Publié dans:Biochemistry
Auteurs principaux: Clark, Michael David, Kumar, Ganesan Senthil, Marcum, Ryan, Luo, Qianyi, Zhang, Yongbo, Radhakrishnan, Ishwar
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564341/
https://ncbi.nlm.nih.gov/pubmed/26274502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00332
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