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Shikonin reduces TGF-β1-induced collagen production and contraction in hypertrophic scar-derived human skin fibroblasts

Hypertrophic scarring/hypertrophic scars (HS) is a highly prevalent condition following burns and trauma wounds. Numerous studies have demonstrated that transforming growth factor-β1 (TGF-β1) plays an essential role in the wound healing process by regulating cell differentiation, collagen production...

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Publicat a:Int J Mol Med
Autors principals: FAN, CHEN, DONG, YING, XIE, YAN, SU, YONGHUA, ZHANG, XUFANG, LEAVESLEY, DAVID, UPTON, ZEE
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4564088/
https://ncbi.nlm.nih.gov/pubmed/26239419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2015.2299
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