Osteoblast-induced osteoclast apoptosis by fas ligand/FAS pathway is required for maintenance of bone mass

The interplay between osteoblasts and osteoclasts has a crucial role in maintaining bone homeostasis. In this study, we reveal that osteoblasts are capable of inducing osteoclast apoptosis by FAS ligand (FASL)/FAS signaling. Conditional knockout of FASL in osteoblasts results in elevated osteoclast...

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Publicat a:Cell Death Differ
Autors principals: Wang, L, Liu, S, Zhao, Y, Liu, D, Liu, Y, Chen, C, Karray, S, Shi, S, Jin, Y
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563780/
https://ncbi.nlm.nih.gov/pubmed/25744024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.14
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