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Less is More: Membrane Protein Digestion Beyond Urea–Trypsin Solution for Next-level Proteomics
The goal of next-level bottom-up membrane proteomics is protein function investigation, via high-coverage high-throughput peptide-centric quantitation of expression, modifications and dynamic structures at systems scale. Yet efficient digestion of mammalian membrane proteins presents a daunting barr...
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Publicado en: | Mol Cell Proteomics |
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Autor Principal: | |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2015
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4563727/ https://ncbi.nlm.nih.gov/pubmed/26081834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.R114.042572 |
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