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Less is More: Membrane Protein Digestion Beyond Urea–Trypsin Solution for Next-level Proteomics

The goal of next-level bottom-up membrane proteomics is protein function investigation, via high-coverage high-throughput peptide-centric quantitation of expression, modifications and dynamic structures at systems scale. Yet efficient digestion of mammalian membrane proteins presents a daunting barr...

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Detalles Bibliográficos
Publicado en:Mol Cell Proteomics
Autor principal: Zhang, Xi
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563727/
https://ncbi.nlm.nih.gov/pubmed/26081834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.R114.042572
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